ISOMED has developed a novel, non-invasive, non-radioactive and convenient breath test kit for the diagnosis of Helicobacter pylori called TAU-KIT.
The principle of TAU-KIT is based on the strong urease activity of Helicobacter pylori. When the labelled 13C-Urea reaches the stomach, the urease enzyme hydrolyses the Urea into ammonia and carbon dioxide labelled with 13C. The CO2 produced is absorbed by the blood vessels, diffused into the lungs and finally exhaled.
This simple breath test method is very convenient. Firstly, the patient administers a citric acid solution, and after 10 minutes exhales a normal breath sample into the reference labelled tube. The 13C substrate is then consumed. After 30 minutes, the patient exhales a second breath sample into the second sample tube. The breath samples are analysed by isotope ratio mass spectrometers.
TAU-KIT is authorized by the Spanish Health Ministry and subsidized by the Spanish National Healthcare System as a pharmaceutical product sold at pharmacies on a medical prescription basis. Internationally, TAU-KIT is sold in over 30 countries worldwide, through a continually growing distribution network.
TAU-KIT can replace an Endoscopy for detecting and monitoring the eradication of Helicobacter Pylori, in other words, by establishing with precision if the patient has been cured.
The advantages of TAU-KIT:
- A non-invasive technique, it avoids endoscopy. - Very cost effective. - It uses the non-radiactive stable isotopes 13C. - Sampling takes 40 minutes. - It does not require the use of specially trained personnel. - It can be used on children, aged from 5 to 17, pregnant women and nursing mothers.
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